Vacuum Centrifugal Concentrator is a commonly used evaporation instrument for RNA/DNA, nucleosides, proteins, drugs, metabolites, enzymes or similar in the fields of molecular biology, biochemistry, genetics, analytical chemistry, quality control, etc. The solvent removal of the concentrated composition of the sample, as well as the concentration or drying of the protein. The sample after centrifugation and concentration treatment can be conveniently used for various qualitative and quantitative analysis of chemical, biochemical, biological analysis, immunoscreening and instrumental analysis.
The vacuum centrifugal concentrator equipment system is mainly composed of a centrifugal host, a cold trap and a vacuum pump. Centrifugal enrichment combines three factors of centrifugation, vacuuming and heat for efficient evaporation of various solvents.
The working principle of the vacuum centrifugal concentrator:
The vacuum centrifugal concentrator is to continuously pump the sample in the state of centrifugation with a vacuum pump, or even close to the vacuum, so that the solvent in the sample can be quickly evaporated, the sample system can be quickly concentrated or dried, and the method can be effectively cooled and filtered. The evaporated solvent was collected.
Centrifugation: The centrifugal force generated by centrifugation prevents bumping and loss of sample. The dried solute is completely deposited on the bottom of the vessel to facilitate complete recovery of the sample.
Vacuum: Accelerate evaporation of the solvent in the concentrator. During the concentration process, the sample is always in a lower than room temperature environment to prevent partial deactivation of the heat sensitive sample. In addition, the vacuum condition prevents oxidation of the sample.
Heat: Accelerate the evaporation rate of the sample. In the absence of external heat, the aqueous solution will freeze during the concentration process. This equipment uses radiant heating technology to compensate for the heat loss during evaporation. Thermal radiation is the most efficient way to heat a sample under vacuum.